Often the call that is placed at 8AM or 6PM will be received by a decision-maker that has more time to talk. And don’t underestimate the value of leaving voicemail messages at night.  These will be the very first messages that your prospect will hear in the morning, thereby increasing the odds of them placing a returned call. I have very good success when doing this during the week and not on the weekends.  In my business I find Realtors are busy selling homes in The Woodlands Texas on weekends!