As of about ten minutes ago, it's been made official the FDIC has closed down California based IndyMac Bank, who was one of the biggest ALT-A lenders over the last couple years. I believe this is the second largest bank failure in US history behind the Continental Illinois Bank failure back in 1984 who had $45B in assets compared to around $32B for Indymac. The FDIC was unable to find a taker for the bank deposits and instead created a holding company (IndyMac Federal Bank) to manage them.
This one could have been seen a mile away but you still got to feel for those holding who had part of the $2B or so in uninsured deposits in the bank. According to several sources there's had been a low scale run on the bank that had resulted in several hundred million in deposits being pulled during the last week pushing them over the edge. Though it was going to happen anyway due to massive losses on mortgages on their balance sheet. They'd been able to stay alive as long as they did mainly by attracting large brokered depositors through offering the highest CD rates in the country. Incidentally many of the banks that offer the highest CD rates tend to be the ones with the biggest looming problems.
Official FDIC announcement here:
http://www.fdic.gov/bank/individual/failed/IndyMac.htm
On a similar note, this should be a reminder to people to make sure to stay under the FDIC insurance limit of $100k (if your lucky enough to have that much in the bank). There will undoubtadly be many other regional banks to follow Indymac down over the next year or two, including some larger the Indymac.