TypePad Pro offers five Classic Layouts with their pro level blogging platform

Why do you care? Because if you plan to customize the appearance of your blog using the "Custom CSS" feature, you need to know the proper name of each layout in order to apply styling to it.....
So, with that in mind, there are the layout names in the same order as pictured above:
.layout-two-column-left
.layout-two-column-right
.layout-three-column
.layout-three-column-right
.layout-one-column
How would you put this to use? Let's say you are using the 3 Column Right layout, with a fluid width** main content column. That widens the entire blog so it takes up the full width of the window. But let's say you'd like a just little bit of padding on each side.
You would enter this line in the Custom CSS editor
.layout-three-column-right #container {padding: 2px 99px 25px 99px;}
If you were using the Two Column Right layout, you would revise that line to read
.layout-two-column-right #container {padding: 2px 99px 25px 99px;}
The padding amounts are applied Top - Right - Bottom - Left ... So I am specifying 2 pixels of padding at the top; 99 pixels of padding at the right side; 25 pixels of padding at the bottom; and 99 pixels of padding at the left side.
** Want to know more about a fluid width main conten column?
I'm with Go-Daddy and still trying to get my blog to come across, don't confuse me anymore...lol