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About the Neighborhood Wissahickon Philadelphia is a mostly residential neighborhood conveniently located along Ridge Avenue in Philadelphia, PA 19128. Wissahickon, sometimes called "The Wissahickon Section of Roxborough" or "The Wissahickon Neighborhood," is bordered by Manayunk, Roxborough, and The Wissahickon Valley Park. Many residents choose to live in the neighborhood for it's convenient access to trails and creek in the (0 comments)