If you find yourself in the Winnsboro, SC area and you're a history buff like me, then you'll probably like to visit the Winnsboro, SC Museum. Winnsboro, SC is located about 30 minutes outside of Columbia, SC and is easily reached from both I-77 and I-20.
The Winnsboro, SC Museum itself is found right on Main Street and can't be missed. The building itself is a part of the history of Winnsboro and staged within it's red brick walls, you'll find tons more history about this small town.
So if you're looking to make a day trip from Columbia, or you're in the Winnsboro area, the check out the museum. They have some wonderful standard exhibits and change out special exhibits on a regular basis.