San Diego is a county of very distinct neighborhoods, micro-climates, micro-real estate markets and neighborhoods' history & personbalities. You really can't talk about San Diego as a whole, unless you're just describing one of the greatest counties in America to live in! We are America's Finest City.
There are many neighborghoods not listed here that, although part of San Diego County, are not part of San Diego proper, as they have incorprated into their own cities, with their own zip codes, post offices, local government, etc., (i.e. Carlsbad & Poway, CA).
Because of where I live, I serve Northern & Northerneastern San Diego. Because of where I work / where my office is I'm also able to serve Eastern, Western & Central San Diego as well as a niche area of the Southern County: the city of Chula Vista.
"Stay Classy San Diego!"