Samuel Guthrie

Managing Real Estate Broker with Fathom Realty PB00068179

Samuel Guthrie was born in Hampden County Massachusetts back in 1782.  I have searched and could not find anything about him until he was 22 when he married Sybil Sexton. He studied at the College of Physicians and Surgeons of New York, (now Columbia University) from 1810 to 1811.  He also attended lectures at the University of Pennsylvania in 1815, which constituted his entire formal education.

In 1817, he moved to Sackets Harbor, New York where he was a rural doctor. He died in 1848, he was 66.

What you may not know about Samuel is that he was also a successful business man and inventor. He manufactured chloric ether, vinegar and priming powder for firearms, making the flintlock muskets obsolete.  He also converted potato starch into molasses and distilled an alcohol.  But he is most noted for the discovery of chloroform independently in 1831.

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Comments (16)

Barbara Todaro
RE/MAX Executive Realty - Retired - Franklin, MA
Previously Affiliated with The Todaro Team

Good morning James Dray ... Samuel Guthrie's most well known for discovering chloroform...

On This Day - Oct 19 : Samuel Guthrie died | Resource | RSC Education

May 18, 2020 02:55 AM
Wayne Martin
Wayne M Martin - Chicago, IL
Real Estate Broker - Retired

Good morning James. Sam was one creative fellow always experimenting. Enjoy your day!

May 18, 2020 03:32 AM
Donald Urschalitz
Lubeck Realty Group - Jupiter, FL
P.A. Realtor ABR RSPS North Palm Beach County

Well I guess you can say he did not stop working after his first accomplishment.

May 18, 2020 04:47 AM
Raymond E. Camp
Howard Hanna Real Estate Services - Ontario, NY
Licensed Real Estate Salesperson Greater Rochester

Good morning James,

Too bad we cannot use chloroform on many of our politicians! Oh and some media as well!

Make yourself an astonishing day.

May 18, 2020 04:48 AM
Roy Kelley
Realty Group Referrals - Gaithersburg, MD

Thank you very much, James, for sharing this interesting story.

Have an outstanding week.

May 18, 2020 04:53 AM
Nina Hollander, Broker
Coldwell Banker Realty - Charlotte, NC
Your Greater Charlotte Realtor

Good morning, James... no doubt that chloroform was a very important invention. Happy Monday to you!

May 18, 2020 05:20 AM
Brian England
Vacasa - Gilbert, AZ
MBA, GRI, REALTOR® Real Estate in East Valley AZ

It sounds like he was more than just a good doctor and I am sure that his family was very proud of his accomplishments.

May 18, 2020 06:43 AM
Nick Vandekar, 610-203-4543
Long & Foster Real Estate Inc 610-225-7400 - Devon, PA
Tredyffrin Easttown Realtor, Philly Main Line

Samuel obviously liked to dabble around with his chemicals, wonder what else he discovered while doing that dabbling.

May 18, 2020 06:48 AM
Michael Jacobs
Pasadena, CA
Los Angeles Pasadena 818.516.4393

Hello James - the world needs more inventors and thought tinkerers in the mix of people.  

May 18, 2020 07:16 AM
Bob "RealMan" Timm
Ward County Notary Services - Minot, ND
Owner of Ward Co. Notary Services, retired Realtor

Wow, Samual was certainly a diverse thinker. I can see why he is not a household name but you would think most of us would have come across his name at one time or another James Dray .

May 18, 2020 08:24 AM
Paul S. Henderson, REALTOR®, CRS
Fathom Realty Washington LLC - Tacoma, WA
South Puget Sound Washington Agent/Broker!

I did not realize that chloroform was that old I thought it was something from the early 20th century. That's why I tune in every morning, to learn...

Happy Monday morning James Dray 


May 18, 2020 08:38 AM
Kathy Streib
Room Service Home Staging - Delray Beach, FL
Home Stager - Palm Beach County,FL -561-914-6224

Wow James- what an inventor!!!!   Have a wonderful week. 

May 18, 2020 10:08 AM
Ron and Alexandra Seigel
Napa Consultants - Carpinteria, CA
Luxury Real Estate Branding, Marketing & Strategy


Chloroform was something I knew about, and so glad you told the rest of the story.  A

May 18, 2020 12:03 PM
Sheri Sperry - MCNE®
Coldwell Banker Realty - Sedona, AZ
(928) 274-7355 ~ YOUR Solutions REALTOR®

Hi James Dray - Sometimes I do my own research to learn more.  I always thought that it was easy to sedate a person quickly using chloroform like they do in the movies.  Come to find out, this is not the case!

May 18, 2020 12:25 PM
Bob Crane
Woodland Management Service / Woodland Real Estate, EXP - Stevens Point, WI
Forestland Experts! 715-204-9671

Hi James, Thanks for sharing this interesting story of Samuel Guthrie.  We are grateful to these creative inventors.  

May 18, 2020 07:50 PM
Jeff Dowler, CRS
eXp Realty of California, Inc. - Carlsbad, CA
The Southern California Relocation Dude

Hi James:

I've certainly heard of chloroform but knew nothing about the inventor - now I know!


May 19, 2020 08:33 AM
John Juarez
The Medford Real Estate Team - Fremont, CA

The varied accomplishments of Samuel Guthrie are truly amazing.


Jun 14, 2020 01:04 PM