Contact/Transaction Management Programs

Here is one of the frustration that I have....For a long time I used a contact/transaction management program that was on my hard drive that I loved.  As I progressed in my career I quit using it because it tied me to on computer at my office, which at the time didn't fit my work style.  Then for about 16 months I paid for Top Producer and never took the time to figure out all of the 'tricks' to make it work.

So what I am looking for is advice on what contact/transaction management program people are using.  I would prefer something online.

Thanks,

Jay